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Needle-less® Growth Factor Serum

Needle-less® Growth Factor Serum

 (2699Reviews)
Regular price $69.99
Regular price $69.99 Sale price $79.99
SAVE 12% Sold out

Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and reveal a more youthful-looking complexion.

  • Clinically shown to improve the look of firmness and texture in 8 weeks
  • Visibly smooths and firms the appearance of skin
  • Revitalizes the look of skin for a more youthful appearance
  • Inspired by the skin’s natural renewal signals to improve the look of elasticity

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Full Description

The problem with most anti-aging serums is simple: they promise results but rarely prove they work. Many claim to smooth, firm, and lift—but where’s the evidence?

When we created Needle-less® Growth Factor Serum, we set out to do things differently. Instead of adding just another product to the lineup, we took a smarter approach—grounded in advanced technology and proven by real clinical testing.

In a 12-week, double-blind, IRB-approved clinical trial, Needle-less® Growth Factor Serum was tested head-to-head against SkinMedica’s TNS Advanced+ Serum, the industry’s best-known growth factor serum (sold at nearly 4x the price). The results spoke for themselves:

Investigator-assessed improvements in skin texture and firmness were significantly higher for Needle-less® at both Week 8 and Week 12
On the Global Aesthetic Improvement Scale (GAIS) at Week 12, Needle-less® Growth Factor Serum showed 30% greater overall improvement than the competitor
It outperformed the leading growth factor serum in 73% of performance indicators


In other words, this isn’t just another serum with empty promises. It’s clinically proven skincare technology that reframes how we approach aging—helping skin look visibly lifted and visibly renewed.

Directions

Apply 1-2 pumps to clean skin in the morning or evening. Can be used daily or as directed by a physician.

Ingredients

Ingredients

Ingredient Highlights: Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Chiretta (Swertia Chirata) Extract, Mushroom (Tremella Fuciformis) Sporocarp Extract



All Ingredients: Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum



DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

Needle-less® Growth Factor Serum

Needle-less® Growth Factor Serum

Regular price $69.99
Regular price $69.99 Sale price $79.99
SAVE 12% Sold out
View full details

    Before and After 12 Weeks Of Use

    When using the Needle-less® Growth Factor Serum as directed. Unedited and not retouched. Results may vary.

    Before

    After

     
     

    4 Reasons You’ll Love Needle-less® Growth Factor Serum

    1. Mimics the Skin's Natural Regenerative Signals

    A blend of 5 bio-engineered growth factor peptides mimics your skin’s repair messengers, encouraging faster cell renewal without the use of human-derived ingredients.

    2. Visibly Lifts & Firms

    Clinically tested to deliver real results. 90% of participants noticed skin felt firmer, improved clarity & tone, and an improvement in overall appearance in just 12 weeks.*

    3. Outperformed the Leading Growth Factor Serum at ¼ the price

    In a 12-week IRB-approved, randomized, double-blinded, controlled clinical trial, our formula delivered 30% greater overall visible improvement, without the $295 price tag.

    4. Repairs & Strengthens Skin Barrier

    This serum features our CeraPep™ Technology, a proprietary blend of ceramides and peptides that restores the barrier’s essential lipids. So not only does this all-new formula lift and firm, but it’s proven to strengthen skin’s barrier after just one use.

    Needle-less" Growth Factor Serum outperformed SkinMedica's $295 TNS Advanced+ Serum in 73%6 of performance indicators

    In head-to-head clinical testing, 90% of participants using DRMTLGY showed overall visible improvement by Week 12 vs. 60% for SkinMedica's $295 TNS Advanced+ Serum

    *Based on a 12 week double-blind IRB-approved clinical trial of20 participants

    Key Benefits

    Visibly Lifts & Firms Skin

    Helps improve the appearance of sagging skin and loss of elasticity.

    Improves Skin Elasticity & Bounce

    Helps skin feel more supple, resilient, and youthful-looking.

    Reduces the Look of Fine Lines & Wrinkles

    Supports smoother, younger-looking skin over time.

    Strengthens the Skin Barrier

    Helps improve resilience and reduce moisture loss.

    Deep, Long-Lasting Hydration

    Hyaluronic acid plumps and hydrates without heaviness.

    Needle-Free Anti-Aging Solution

    Advanced performance—no injections, no downtime.

    • Environment

    • Texture

    • Wrinkles

    • Firmness

      • Normal

      • Dry

      • Combination

      • Oily

        THE SCIENCE BEHIND THE FORMULA

        Dr. Dayan on Needle-less® Growth Factor Serum:

        In this 12-week clinical study, participants were split into two groups—each applying a different topical treatment twice daily. Preliminary results showed visible improvements in wrinkles, texture, and firmness across both groups. One group used DRMTLGY's product, while the other used SkinMedica’s TNS Advanced+ Serum priced 4x more. However, the formula developed by DRMTLGY demonstrated notably superior results in skin texture and firmness.

        Dr. Steven H. Dayan
        MD, FACS

        • Cleanser

        • Toner

        • Serum

        • Treatment

        • Moisturizer

        • Sunscreen

          • Cleanser

          • Toner

          • Serum

          • Eye Cream

          • Treatment

          • Moisturizer

            Frequently Asked Questions

            What does “needle-less” mean?

            The serum delivers advanced skin-renewing ingredients topically—no injections or procedures required.

            Can I use this with retinol or vitamin C?

            Yes. Apply this serum first, then layer other actives as tolerated.

            Is this safe for sensitive skin?

            The formula is designed to be gentle, but patch testing is recommended.

            How long before I see results?

            Many users notice improved hydration quickly, with visible firmness and smoother skin after several weeks of consistent use.

            • ★★★★★

              Noticeable difference

              I started using this product a few weeks ago and can already see a reduction in fine lines.

              R.

            • ★★★★★

              I like it

              I've been using this for a week or so now and I like the consistency and the way it soaks into my skin nicely. I have not used it long enough for results yet, but I do like the feel of this serum and how it preps my skin.

              Korrie Wo

            • ★★★★★

              A total must-have in any skincare routine

              This serum is absolutely amazing! From the very first uses, my skin felt firmer, smoother, and more radiant.

              Linoska Boltbox Aguillon

            • ★★★★★

              Silky

              Silky and has transformed my skin. It's radiant and buttery smooth! I've used it with the peptide night cream as my first order from here about 2 weeks ago.

              Liz

            • ★★★★★

              Lovely

              Absolutely loving this serum it melts into my dry skin like silk, delivering hydration, a refreshed feel, and a gentle lift that makes all the difference

              Krista Johnson

            • ★★★★★

              The glow and firmness I was looking for

              I’ve been using the Needle-less® Growth Factor Serum from DRMTLGY for a few weeks now, and it has honestly become one of my favorite skincare products.

              Nataliia